Bioreactors
Specialized equipment for biotechnological processes, fermentations and cell cultures with total control of bioprocess variables.
Benefits
- Design according to ASME BPE.
- Control of O2, CO2, pH, temperature and agitation.
- High purity interior finish (very low roughness).
- Integration with advanced instrumentation.
Functionality / Applications
Types of industrial bioreactors
1. Biorreactores discontinuos (Batch)
- The medium and microorganisms/cells are loaded at the beginning.
- Nothing is added or removed until the process is complete.
- Simple control.
- Widely used in fermentation, basic cultures and batch production.
2. Semi-continuous bioreactors (Fed-Batch)
- It begins with a batch culture.
- Then the substrate is added in a controlled and progressive manner.
- It allows for growth control, avoidance of inhibitions, and increased productivity.
- It is the most commonly used type in industrial biotechnology (enzymes, proteins, drugs).
3. Continuous bioreactors
- Constant feeding and continuous extraction of the product.
- They maintain the crop in a steady state.
- High productivity and efficiency.
- Widely used in large-scale bioprocesses and continuous fermentations.
4. Stirred Tank Reactors (STR)
- The most common ones in the industry.
- They use mechanical agitators.
- Ideal for homogeneous mixtures and precise control.
5. Bubble column bioreactors
- They don't have agitators.
- Mixture achieved by aeration.
- Common in biomass production and aerobic crops.
6. Air-lift bioreactors
- Circulation generated by differences in air density.
- Lower shear stress.
- Ideal for sensitive cultures (animal or plant cells).
7. Membrane bioreactors
- They separate biomass and product through filtration.
- Widely used in water treatment and continuous bioprocesses.
8. Fixed bed or fluidized bed bioreactors
- They support immobilized microorganisms.
- High cell density.
- Common in specialized fermentations and residual bioprocesses.
